Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry


Microwave assisted synthesis and characterization of 1-[4-(3-substitutedacryloyl)-phenyl]-pyrrole-2,5-diones

Author(s): K. Aravind and A. Ganesh

A series of 1-[4-(3-Substituted-acryloyl)-phenyl]-pyrrole-2,5-diones(5a-f) were synthesized and characterized. All the compound synthesized from 1-(4-Acetyl-phenyl)-pyrrole-2,5-dione(3) and substituted benzaldehydes(4a-f) by using Claisen-Schmidt Condensation reaction under conventional heating method and microwave irradiation methods. All the compoundswere characterized based on spectroscopic analysis such as IR, 1H-NMR and Mass spectral data.