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Microwave assisted synthesis of styrylisoxazoles under solvent free conditions | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X

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Abstract

Microwave assisted synthesis of styrylisoxazoles under solvent free conditions

Author(s): Vijender Goel

Keeping in view of utility of Microwave induced Organic Enhancement (MORE) chemistry, microwave induced preparation of 1- (2-hydroxy phenyl) -5- phenyl - 4-pentene- 1,3- diones in a single pot reaction is reported which on condensation with hydroxylamine hydrochloride under microwave irradiation afforded 3- (2- hydroxyphenyl) –5- styrylisoxazoles in only 100 sec. These compound were characterized on the basis of elemental analysis, IR and NMR spectral data.


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