Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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Microwave Assisted Synthesis, Physicochemical & Spectral Characterization of Common Molecules

Author(s): Ambatkar MP, Rathi LG, Rokde VV, Danao KR, Mahajan UN

Some common molecules like antipyrine and toluene-p-sulphonamide have been synthesized by Microwave Assisted method i.e. “Green Synthesis”. The reaction yields were compared with reported conventional method. The purpose of this study was increasing practical yield, lowering the reaction time and reducing pollution. The products were characterized by various techniques like melting point, Thin Layer Chromatography (TLC), partition coefficients, dissociation constants, % ionization, Fourier Transform Infrared (FTIR) spectroscopy, Mass and Proton Nuclear Magnetic Resonance (1H-NMR) spectroscopy.

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