Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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Abstract

Microwave synthesis and antimicrobial activity of some N-aryl hydrazones

Author(s): Bharat Parashar, Sudhir Bharadwaj, Vinod K. Sharma and Pinki B. Punjabi

-N-arylhydrazone derivatives of N-phenyl anthranilic acid are pharmacologically active and are very useful. A number of hydrazide derivatives have been synthesized by the condensation of the hydrazide with the numbers of aromatic aldehydes and ketones in the presence of conc. hydrochloric acid as a catalyst. The reactions have been carried out under microwave irradiation. The structures of the products were confirmed by physico-chemical and spectral data like IR, NMR and Mass.


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