Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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Abstract

Mixed ligand stability constants of Co (II), Ni (II), Cu (II) and Zn (II) transition metal complexes with chloropheniramine maleate drug and amino acids

Author(s): B. K. Magare and M. B. Ubale

Chemical equilibrium studies on Co (II), Ni (II), Cu (II) and Zn (II) transition metal complexes with chloropheniramine maleate drug (L) and a series of eight amino acids (R) have been investigated pH metrically at 270C temperature and 0.1 M ionic strength (NaClO4) in aqueous solution. The formation of various possible complex species has been evaluated by computer program and discussed in terms of various relative stability parameters.


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