Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

Abstract

Mixed ligand stability constants of Co (II), Ni (II), Cu (II) and Zn (II) transition metal complexes with chloropheniramine maleate drug and amino acids

Author(s): B. K. Magare and M. B. Ubale

Chemical equilibrium studies on Co (II), Ni (II), Cu (II) and Zn (II) transition metal complexes with chloropheniramine maleate drug (L) and a series of eight amino acids (R) have been investigated pH metrically at 270C temperature and 0.1 M ionic strength (NaClO4) in aqueous solution. The formation of various possible complex species has been evaluated by computer program and discussed in terms of various relative stability parameters.


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