Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

Abstract

Molecular Interaction of NSAID in Protic and Aprotic Solvent Mixture-An Acoustical and Viscometric Study

Author(s): Sunil kumar Pradhan, Ashok Kumar Sahoo, Monalisa Das, Smrutiprava Das, Ajay Kumar Patnaik

The density (ρ), viscosity (Ƞ) and ultrasonic velocity (U) of non-steroid anti-inflammatory drug was measured in the mixture of DMSO and methanol at 303.15 K. Based on this measurement the values of different volumetric as well as acoustic parameters were calculated. The results are discussed in terms different interactions with protic and aprotic solvent media and structural effect between the solvents over a wide range of concentration.


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