Novel pyrimidinone derivative as potential promising antimicrobial agent | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X


süperbetin giriş

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

agariookey oyna istanbul okey


Novel pyrimidinone derivative as potential promising antimicrobial agent

Author(s): Vikas Kumar, Pratibha Singh

Some new derivatives of 4-phenyl-5-[5'-(3''-chloro-2''-oxo-4''-substitutedaryl-1''-azetidinyl)- 1',3',4'-oxadiazol-2'-yl]-6-methyl-3,4-dihydropyrimidine-2-one and 4-phenyl-5-[5'-(2''- substitutedaryl- 4' '-oxo -1'',3''- thiazolidin -3''-yl) -1',3',4 '-oxadiazol-2'-yl]- 6- methyl-3,4- dihydro pyrimidin -2-one have been synthesized by reacting different substituted Schiff bases with chloroacetyl chloride and thioglycolic acid, respectively. The structures of synthesized compounds were confirmed by IR and 1H-NMR data. Antimicrobial activities of compounds were investigated using the standard method against different bacterial and fungal strains in comparison with standard drugs. Microbiological results indicated that the synthesized compounds possess a board spectrum of activity.


rokettube brazzers

Turkish dental care is known to be affordable compared to other countries. If you want an affordible dentist Turkey, check out periodonta. It is heavily recommended for dental patients visiting Turkey