Novel Route of Synthesis of Some Trientine Impurities and Their Characterization | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
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Novel Route of Synthesis of Some Trientine Impurities and Their Characterization

Author(s): Saibal Kumar Das*, Varsha Venkaiahgari, Ravinder B, Manoj Kumar Dubey and Rakeshwar Bandichhor

Trientine has been tested for inhibition of the spontaneous development of hepatitis and hepatic tumours in rats. It has been described in the use of copper binding compounds in the treatment of various disorders, including treatment of diabetes mellitus and complications thereof, including diabetic cardiomyopathy. We hereby wish to report first synthesis of Impurities A, B, C, D, E, G and H along with Impurity F via innovative approach starting from cheap raw materials.

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