Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Novel thiazolidine-2,4-dione mannich bases: Synthesis, characterization and antimicrobial activity

Author(s): Prajwal L. Lobo, Boja Poojary, Manjunatha K, Prathibha A, N. Suchetha Kumari

A series of novel (5E)-5-arylidene-3-substituted-1,3-thiazolidine-2,4-diones were prepared by treating 1,3- thiazolidine-2,4-dione with substituted aromatic aldehydes in the presence of sodium acetate followed by Mannich reaction with primary/secondary amines. Structures of the newly synthesized compounds were assigned on the basis of elemental analyses, IR, 1H NMR and mass spectral studies. The newly synthesized compounds were tested for their in vitro antibacterial and antifungal activity against a variety of microorganism.


PDF

FIND ARTICLES
SCImago Journal & Country Rank
Recommended Conferences
bornova escort karşıyaka escort osmangazi escort buca escort anne porno fetiş porno anal porno bartın escort burdur escort eskişehir escort escort izmir bursa escort porno escort bayan