One-pot three-component synthesis of chromeno[4,3-d ]pyrimidinone derivatives | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
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One-pot three-component synthesis of chromeno[4,3-d ]pyrimidinone derivatives

Author(s): Amar Djemoui * 1,2 , Malika Leguil 1 , Lahcène Souli 1 , Naouri Abdelkader 3 and Mokhtar Boualem Lahrech 1

A simple, efficient, and general methods has been d eveloped for the One-pot three-component reaction o f salicylaldehyde 1,3-dicarbonyl compounds and 2-Amin obenzimidazole in the presence of catalytic amounts of piperidine in acetic acid led to a chemo selective synthesis of chromeno[4,3-d]pyrimidine-6-one deriv atives, in good yields.


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