Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry


PEG Mediated Eco-Friendly One Pot Synthesis of β-Amino Carbonyl Compounds under Ambient Temperature Conditions

Author(s): Amel Zetchi, Boudjemaa Boumoud, Taoues Boumoud and Abdelmadjid Debache

Various β–amino carbonyl derivatives were synthesized, by the reaction of aniline, acetophenone and aromatic aldehydes, in high yields within shorter reaction times using PEG-600 as a safer catalyst under solvent-free conditions at room temperature. This synthetic route is exceedingly easy and avoids the use of toxic catalysts.