Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry


Phenolic constituents and biological activity of the genus pluchea

Author(s): Sayed A. Ahemd and Emadeldin M. Kamel

The genus Pluchea is belonging to the family Asteraceae and comprises about 90 species distributed mainly in North and South America, Africa, Asia and Australia. The extracts from the species of the genus Pluchea have been used as antioxidant, hepatoprotective, cytotoxic, antiulcer, antipyretic, antibacterial, antifungal, antiviral, Antinociceptive, Anti-amoebic and for venom neutralization. Phytochemical screening of species of the genus Pluchea revealed the presence of flavonoids, tannins, alkaloids, eudesmane-type sesquiterpenoids, monoterpenes, lignan glycosides and triterpenoids. This review summarizes the previously evaluated biological activities of the extracts of species of the genus Pluchea as well as the previously isolated phenolic compounds.