The oxidation induced by free radicals results in many degenerative disease. The purpose of this study to determine phenolic and flavonoid content, antioxidant activities of ethylacetate extract (EAE) of Litsea cubeba (Lour.) Pers. barks. Phenolic and total flavonoid contents in EAE was determined by colorimetric methods. EAE was found to contain high levels of phenolic (84.26 ± 0.57 mg GAE/g), total flavonoid (52.81 ± 0.03 mg QE/g). Antioxidant activity from DPPH assay measured as IC50 was 166.90 ± 0.10 μg/mL. The results reveal that EAE of Litsea cubeba barks has strong antioxidant potential. Our further study is to explore the mechanism action of EAE.