Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry


Physicochemical Characterization of Mixed Ligand Complexes of O and N Donar Ligands

Author(s): Shirode PR, Agrawal RK, Yeole PM, Manke AP, Suralkar RS

The mixed ligand complexes of the type M(L1L2)Cl2, where, M=Cobalt(II), nickel(II) and copper(II). While, L1=O-hydroxy acetophenone oxime and L2=Salicylaldehyde semicarbazone have been prepared by reacting equimolar quantities of transition metal(II) chloride with two ligands L1 and L2. These synthesized complexes have been studied on the basis of elemental analysis, analysis of UV and IR, conductivity measurement, magnetic measurement, thermal analysis and antimicrobial activities. Analysis of results shows octahedral geometry of the complexes. The complexes show electrolytic nature and having more antimicrobial activity than the ligands. The central metal ion is bonded to ligands through oxygen and nitrogen.