Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry


Phytochemical Screening and Antimicrobial Activity of Shuteria involucrate

Author(s): Isaiah S, Senthamizh Selvan N

Shuteria involucrata belongs to fabiaceae family is one of the highly potential Indian medicinal plant with wide range of pharmaceutical applications which includes dental diseases. In the present work the plant extract of Shuteria involucrata is investigated for its phytochemical and antimicrobial characteristics. The dry plant material was successively extracted using various solvents such as chloroform, ethanol, hexane, methanol, and petroleum ether in soxhlet apparatus. All extracts were concentrated by rotary vacuum evaporator and were screened for major phytochemical compounds using established procedures. Around ten phytoconstituents were identified to be present. The antimicrobial activity were carried out by disc diffusion technique against the six selected pathogens. Among the six, tested for Antimicrobial Activity Staphylococcus aureus, Pseudomonas aeruginosa and Candida albicans were more susceptible to the extract, whereas the others are less susceptible. Ethanol, methanol and water extracts of plant materials exhibited good antimicrobial activity against gram positive, gram negative bacteria and fungus.