Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

Abstract

Phytochemistry and Medicinal Value of Harad (Terminalia chebula Retz.) the ‘King of Medicinal Plants’

Author(s): Narendra Kumar, Paul Khurana SM

Terminalia chebula, popularly known as Harad, black- or chebulic myrobalan contains hydrolysable tannins. This dominantly contains many phytochemicals viz., casuarinin, chebulanin, chebulagic acid, chebulinic acid corilagin, ellagic acid, gallic acid, neochebulinic acid, punicalagin, 1,2,3,4,6-penta-O-galloyl-β-D-glucose,1,6-di-o-galloyl-D-glucose,3,4,6-tri-o-glloyl-D-glucose, terchebulin. There are many medicinal investigations recording viz., antiulcer, antioxidant, anticarcinogenic, antimutagenic, radio protective, hepatoprotective, cardioprotective, cytoprotective, antidiabetic, renoprotective, antibacterial, antifungal, antiviral, antiprotozoal, anti-inflammatory, antiarthritic, antispasmodic, wound healing and anticonceptive, molluscidal, anthelmintic, anaphylactic, hypolipidemic, hypocholesterolemic. Also having chemopreventive potential and adaptogenic activities. This has purgative property, immunomodulatory, analgesic, antiallergic, neuroprotective, acetylcholine inhibition activity and have gastrointestinal motility improving activity. This is beneficial in bronchial asthma and also useful as dye for fabrics.


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