Plantago belongs to the Plantaginaceae family, with two species known as Plantago ovate Forsk and Plantago psyllium L. In herbal medicine Plantago husk powder is commonly as laxative. Application of Psyllium husk as a hydrocolloid fiber has been almost confirmed in treatment of diabetes type 2. Recent researches on Plantago indicate the effect of its fibers on reducing cholesterol, blood lipid and blood glucose of people with diabetes and reducing the risk of colon cancer. There are no side effects reported for patients under treatment with Plantago fiber. Regarding the fact that Psyllium is widely used, different aspects of it is discussed in the present study.