Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
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Abstract
Polyethylene glycol mediated catalyst-free synthesis of 5,9b-dihydro-1H- [1,2,4] triazino[5,6-b]indole-3-ols/thioles
Author(s): R. Sridhar,M. Yedukondalu, K. R. S. Prasad and M. V. Basaveswara RaoAn efficient one pot environmentally benign chemical synthesis of 5,9b-dihydro-1H-[1,2,4] triazino [5,6-b] indole-3- ols and 5,9b-dihydro-1H-[1,2,4] triazino [5,6-b] indole-3-thiols is carried out in PEG as a recycle reaction medium under neutral conditions by using isatin, and semicarbazide/thiosemicarbazide. No additional base or solvents are utilized.
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