Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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Potentiometric studies on mixed ligand complex formation copper (II) complexes with enalpril maleate and some amino acids

Author(s): Suresh T. Gaikwad, Aanjali S. Rajbhoj and Balasaheb R. Arbad

Potentiometric investigation on mixed ligand complex formation of copper (II) ion with (S)-1-[N-[1- (ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-L-proline (enalpril maleate) as primary ligand and a series of eight amino acids as secondary ligand was made at 27 ± 0.1°C and ionic strength of 0.1 M NaClO4 in aqueous medium by Irving-Rossoti technique. Formation constant have been calculated by using computer program SCOGS.


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