Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry


Potentiometric studies on mixed ligand complex formation copper (II) complexes with enalpril maleate and some amino acids

Author(s): Suresh T. Gaikwad, Aanjali S. Rajbhoj and Balasaheb R. Arbad

Potentiometric investigation on mixed ligand complex formation of copper (II) ion with (S)-1-[N-[1- (ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-L-proline (enalpril maleate) as primary ligand and a series of eight amino acids as secondary ligand was made at 27 ± 0.1°C and ionic strength of 0.1 M NaClO4 in aqueous medium by Irving-Rossoti technique. Formation constant have been calculated by using computer program SCOGS.