Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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Abstract

Radical scavenging and Antioxidant activities of three extracts of Lavandula coronopifolia grown in El-Hoggar, Tamanrasset, Algeria

Author(s): Brahim LABED, Abdelaziz BOUHRIRA, Kheira BENAISSA and Noureddine GHERRAF

The genus Lavandula (common name Lavender) involves 39 species of flowering plants in the Lamiaceae family. The present study deals with the antioxidant activity of three different solvent extracts of Lavandula coronopifolia that grows in Hoggar (Tamanrasset) south of Algeria. The radical scavenging potential was determined on basis of the activity of trapping the stable 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. The values of IC50 (mg/mL) were found to be 0.0347g/L, 0.0414g/L and 0.0910g/L for diethyl ether, ethyl acetate and n-Butanol extracts respectively, compared to the ascorbic acid (VC) and the tocopherol acid (VE) which were 0.0088g/L and 0.0154 g/L respectively. Moreover, the FRAP (Ferric reducing antioxidant power) assay was carried out and revealed a better efficacy of ethyl acetate extract than the other extracts. By using VCEAC (Vitamin C Equivalent Antioxidant Capacity), it is found that the reduction percentages are: 0.90 g/L, 0.680 g/L and 0.304 g/L for Diethyl ether, Acetate ethyl and n-Butanol respectively. The ascorbic acid (VC) considered, as a positive test has a VCEAC of 1.223g/L.


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