GET THE APP

Rapid, Economical and Green Solid Oxidation of Sulfides to Sulfones and Their Antimicrobial Evaluation- Part 2 | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

Abstract

Rapid, Economical and Green Solid Oxidation of Sulfides to Sulfones and Their Antimicrobial Evaluation- Part 2

Author(s): Anil M. Manikrao, Dinesh R. Chaple, Niranjan S. Mahajan, Prafull M. Sabale

The sulfones (IIa-k) of various 3-(N-substituted carboxamidoethylthio)-(4H)-1, 2, 4-triazoles (Ia-k) were synthesized by highly selective oxidation method using oxone®. Through this solid state “Green” oxidation technique, the titled compounds were obtained in good purity and high yields. The structures of the synthesized compounds were confirmed using IR, 1H-NMR spectra and elemental analysis. All the compounds were screened for their antibacterial and antifungal activities. Almost all the compounds showed comparable antibacterial and antifungal activities with that of standards, but none of them found to possess promising these activities. The oxidation system was found clean, safe, operationally simple, and environmentally friendly method. Thus it meets the needs of contemporary “Green Chemistry” and found suitable for practical synthesis.


PDF

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Google Scholar citation report
Citations : 23677

Der Pharma Chemica received 23677 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry