Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

Abstract

Reduction of Alfatoxin in grey mullet By Ginseng Extract and probiotic

Author(s): Mona S. Zaki, Olfat M. Fawzi and Sami S. Shalaby

Aflatoxine the major toxic metabolites of fungi which are able to induce chronic liver damages. The antioxidant and hepatoprotective effects of Ginseng extract and probiotic on Alfatoxin was investigated. Alfatoxicosis causes significant increase in liver enzyme SGOT and SGPT, Alkaline phosphatase activity and an increase in the level of cholesterol total lipid, decrease the level of total protein and hemoglobin and P.C.V. Moreover the liver exhibited some clinicopathological changes and decreased body weight. Both Ginseng extract and probiotic reduced the development of hepatotoxicity by Aflatoxin. probiotic showed more improvement of all enzymes of kidney and liver, and also total lipid and cholesterol were reduced and dody weight increased


PDF