Review of HPLC/UPLC-UV Methods for Sensitive Determination of Nicotine in Plasma | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.


Review of HPLC/UPLC-UV Methods for Sensitive Determination of Nicotine in Plasma

Author(s): Bassam M Ayoub, Mona G Arafa and Moataz S Hendy

A concise review of HPLC/UPLC-UV methods for determination of nicotine in human plasma is presented in this manuscript in the form of tables with full description of the used stationary phases, mobile phases, detection wavelength, flow rate and linearity ranges. Also full description of plasma extraction techniques is described for all the reported LC-UV methods. This review permits the application of the reported methods for further pharmacological and clinical studies while design of new nicotine formulations. The reported methods may also be used in comparative studies using different dosage forms and cigarettes to investigate the pharmacokinetic parameters of new nicotine formulations in vivo.


Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Google Scholar citation report
Citations : 25868

Der Pharma Chemica received 25868 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry