Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

RP-HPLC Method for Estimation of Nitazoxanide in Oral Suspension Formulation

Author(s): Jimish R Patel, Harpreet Singh Bedi, Anil Middha, Laxman M Prajapati, Vijay K Parmar

A simple, precise, accurate, rapid and reproducible reverse phase high performance liquid chromatographic method was developed for estimation of Nitazoxanide in oral suspension formulation. The mixture of acetonitrile: ammonium dihydrogen phosphate buffer (0.075 M) in the ratio 45:55 (% v/v) adjusted to pH 3.0 with orthophosphoric acid was used as mobile phase. The detection of the Nitazoxanide in oral suspension formulation was carried out at 240 nm and flow rate was set to 1.5 ml/min. Linearity was obtained in the concentration range of 5 to 25 μg/mL of Nitazoxanide with correlation coefficients of 0.997. The results of the analysis were validated statistically and recovery studies confirmed the accuracy of the proposed method.


PDF

FIND ARTICLES
SCImago Journal & Country Rank
Recommended Conferences
bornova escort karşıyaka escort osmangazi escort buca escort anne porno fetiş porno anal porno bartın escort burdur escort eskişehir escort escort izmir bursa escort porno escort bayan