Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.


RP-HPLC method for the determination of Valacyclovir in bulk and Pharmaceutical formulation

Author(s): M Sugumaran, V Bharathi, R Hemachander and M Lakshmi

A reverse phase high performance liquid chromatography (RP-HPLC) has been developed for the estimation of valacyclovir in bulk drug and pharmaceutical dosage form. The quantification was carried out using C18 column and mobile phase consisting of 0.067 M phosphate buffer at pH 6.5: acetonitrile : methanol (70:20:10 % v/v), at flow rate of 0.5 mL/min. The separation was performed at ambient temperature. Eluents were monitored by UV detector set at 244 nm. The method was statistically validated for the linearity, precision, accuracy, LOD and LOQ. The linearity was found to be in the range of 5-30 μg/mL. The proposed method was found to be simple, precise, accurate, rapid, economic and reproducible for the estimation of valacyclovir in bulk drug and tablet.


SCImago Journal & Country Rank
Recommended Conferences
bornova escort karşıyaka escort osmangazi escort buca escort anne porno fetiş porno anal porno bartın escort burdur escort eskişehir escort escort izmir bursa escort porno escort bayan