Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry


Samarium Chloride: An efficient catalyst synthesis of 1,4-dihydropyridines (Hantzsch pyridines)

Author(s): Y. P. Sarnikar, Y. D. Mane, S. M. Survarse and B. C. Khade

Samarium trichloride catalyzed one-pot synthesis of dihydropyrines has been developed. The methodology was successfully applied to various aldehydes. All the reactions were carried out at acetonitrile reflux.