GET THE APP

Seroprevelence of antibodies to human platelet antigens in pregnant women in OSOGBO | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X

ilbet

süperbetin giriş

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

agariookey oyna istanbul okey

Abstract

Seroprevelence of antibodies to human platelet antigens in pregnant women in OSOGBO

Author(s): Olayanju A.O, Akanni E.O, Akinseye J.F, Akele R.Y, Eluke B.C, Olayanju A. J and Enitan S.S.

Human platelet antibodies are often implicated in some disease conditions, such as neonatal alloimmune thrombocytopenia (NAIT), idiopathic thrombocytopenic purpura (ITP) and platelet refractoriness. There is paucity of information on the development and relevance of this antibody in pregnant black women, especially in Nigeria. This study was therefore designed to determine the occurrence of antiplatelet antibody in pregnant women. Eightynine (89) pregnant women attending a tertiary health facility in Osogbo participated in the study. Platelet count and human platelet antigens (HPA) were investigated using standard protocols of automation and ELISA respectively. Thirty-two(34%)of the women were thrombocytopenic and antiplatelet antibody was detected in 17(53%) of this sub-set. The antibody was of higher frequency in multiparous women and more prevalent within the age group of 26-30, especially those with history of previous blood transfusion. The study shows the imperativeness of including the platelet quantitative and functional assays as part of routine antenatal testing and monitoring.


PDF

rokettube brazzers

Turkish dental care is known to be affordable compared to other countries. If you want an affordible dentist Turkey, check out periodonta. It is heavily recommended for dental patients visiting Turkey