Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry


Simple and efficient microwave assisted PEG mediated synthesis of Pyrazole analogues of Curcumin

Author(s): M. G. Shioorkar and M. B. Ubale

Pyrazole Curcumin was synthesized by using Microwave irradiation technique in Polyethylene Glycol-400 (PEG- 400) as solvent. One mole of Curcumin and 1.5 moles of substituted hydrazine when irradiate corresponding curcumin pyrazole derivatives were obtained in good yield. This method is eco friendly, time saving, productive and easy to workup.