GET THE APP

Simple Extractive Spectrophotometeric Determination of Amphetamine Sulphate by Acid Dye Complexation in Solid Dosage Form | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

Abstract

Simple Extractive Spectrophotometeric Determination of Amphetamine Sulphate by Acid Dye Complexation in Solid Dosage Form

Author(s): Kalkotwar R. S, Kasture A. V, Pattan S. R, Dengale S. S, Dighe N.S

Simple, accurate, rapid and highly sensitive Extractive Spectrophotometeric determination method has been developed and validated for estimation of Amphetamine Sulphate in pharmaceutical solid dosage form. The proposed method is based on the principle that Mono and diamines in the dissociated form (Ion) combined with dissociated form of the Acid dye Solochrome black T. The formation of Acid dye complex has been evaluated by carrying TLC, Infra-red spectra. The acid dye-drug complex has lmax at 520 nm. Beer’s Lambert Law obeyed in the range of 20-100μg ml-1. The results were validated statistically. The further scope for this method is that it can be applied to body fluid in cases of intoxication.


PDF

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Google Scholar citation report
Citations : 23677

Der Pharma Chemica received 23677 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry