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Simultaneous estimation of Nebivolol and S-Amlodipine in tablets by UV-Spectrophotometry | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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Abstract

Simultaneous estimation of Nebivolol and S-Amlodipine in tablets by UV-Spectrophotometry

Author(s): Joshi Hirak.V, Dr.Patel J. K, Patel M. P, Wankhede S

The present work describes a simple first derivative spectrophotometric method for simultaneous estimation of nebivolol and s-amlodipine in tablets. The wavelengths selected for analysis were 242.0 nm and 290.0 nm for s-amlodipine and nebivolol, respectively. Both nebivolol and samlodipine were found to obey Beer’s law over the concentration range of 0-60 μg/ml at selected wavelengths. The proposed method was validated statistically and by recovery studies.


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