Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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Abstract

Simultaneous voltammetric measurement of ascorbic acid and dopamine at poly (vanillin) modified carbon paste electrode: A cyclic voltammetric study

Author(s): J. G. Manjunatha,B. E. Kumara Swamy, M. Deraman and G. P. Mamatha

Polymerized film of vanillin was prepared on to the surface of carbon paste electrode in alkaline solution by cyclic voltammetric (CV) technique after pretreatment by H2SO4 media. The poly vanillin (VA) film coated carbon paste electrode (CPE) exhibited excellent electrocatalytic activity toward the oxidation of dopamine (DA) and ascorbic acid (AA) in 0.2M acetate buffer solution at pH 7. This modified electrode exhibited a potent and persistent electron-mediating behavior followed by well-separated oxidation peaks towards DA and AA. The modified electrode shows good sensitivity, selectivity and stability and has been applied to the determination of DA and AA


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