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Solvent-free synthesis, characterization and antimicrobial activity of complexes of 2-hydroxybenzoic acid hydrazide with some M(II) chlorides (M= Co and Ni) | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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Abstract

Solvent-free synthesis, characterization and antimicrobial activity of complexes of 2-hydroxybenzoic acid hydrazide with some M(II) chlorides (M= Co and Ni)

Author(s): H. A. Salami, A. U. Haruna, F. T. Ezeala and O. W. Salawu

This work describes the synthesis and in vitro studies on complexes of 2-Hydroxybenzoic hydrazide (HBH with Nickel(II)Chloride and Cobalt(II)Chloride. The 2-Hydroxybenzoic hydrazide (HBH) ligand was prepared by a solvent-free method. The chelates were characterized by elemental analysis, molar conductance and spectral studies. The antimicrobial activities of the ligand and their metal chelates have also been screened.


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