Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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Spectral study and antimicrobial activity of Co (II), Cu (II), Mn (II), Ni (II) and Zn (II) Complexes of bisazo dye derived from Meta phenylene diamine

Author(s): Anitha, KR Venugopala Reddy, Vittala Rao KS, Fasiulla, AM Sridhara and Shobha KS

In the present study, bisazo dye 2, 21 [benzene-1, 3-diyl di(E) diazene 2,1-diyl] bis (4- nitroaniline) has been synthesized by the diazotization and coupling of Meta phenylene diamine with 4-nitroaniline. Further azo metal (II) complexes of Co, Cu, Mn, Ni and Zn have been synthesized. The ligand and all the metal complexes were characterized by various physicochemical techniques like elemental analysis, electronic, Infrared, Proton NMR and TGA. The metal chelates have metal to ligand ratio of 1:1. All the synthesized compounds were screened for antimicrobial activity.


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