GET THE APP

Spectrophotometric estimation of guaifenesin and salbutamol in pure and tablet dosage form by using different methods | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

Abstract

Spectrophotometric estimation of guaifenesin and salbutamol in pure and tablet dosage form by using different methods

Author(s): Amruta A. Bankar, Sonu R. Lokhande, Sawant R. L. and Ankita R. Bhagat.

Two simple, precise, accurate and economical UV spectrophotometric methods have been developed and validated for routine estimation of Guaifenesin and Salbutamol in tablet dosage form. Spectroscopic studies were carried out using double beam U.V.Spectrophotometer model JASCO. The marketed combination of Guaifenesin and Salbutamol that is salbusum forte from Local market. Method A employs formation and solving of simultaneous equation using 274 nm and 279 nm as two analytical wavelengths for both drugs in Distilled water, Whereas Method B involved formation of Q-absorbance equation at isobestic point ( 253 nm). Guaifenesin and Salbutamol shows Linearity in a concentration range of 10-50μg /ml. Recovery studies for guaifenesin 97.99 % and 99.22 % for salbutamol in case of simultaneous equation method confirming the accuracy of the proposed method.


PDF

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Google Scholar citation report
Citations : 15261

Der Pharma Chemica received 15261 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry