Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry


Spectrophotometric study of stability constants of Semicarbazone-Cu(II) complex at different temperatures

Author(s): MA Hussien and HM Salama

The formation of cupper(II) complex with semicarbazone has been studied spectrophotometrically at an absorption maximum of 700 nm at different temperatures. The data shows that copper(II) and famotidine combine in the molar ratio of 1: 1 . The stability constants of the complex were calculated to be 9.33 ×104 , 8.51 ×104 , and 7.41 ×104 by continuous variation method and 3.28×105 , 3.05×105, and 2.53 ×105 by mole ratio method at 30o, 40o, and 50o C, respectively.