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S ynthesis of 1-alkyl succinimidoanthracenyl-4-((naph thalene-1-yloxy)methyl)- 1H-1,2,3-triazoles | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
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Abstract

S ynthesis of 1-alkyl succinimidoanthracenyl-4-((naph thalene-1-yloxy)methyl)- 1H-1,2,3-triazoles

Author(s): J. Ramchander

Regioselective synthesis of a series of 1,4-disubst ituted of 1-alkyl succinimidoanthracenyl-4-((naphthalene-1- yloxy)methyl)-1H-1,2,3-triazoles employing click reaction is presented. Highly selec tive and efficient copper(I)- catalysed 1,3-dipolar cyclo addition between 1-naph thylpropargylic ether and azido alkyl succinimidoanthracenyl yielded the title compounds in 74% to 94%. The stru cture of all the new 1,2,3-triazoles was characteri zed by 1HNMR,13C NMR, IR and Mass.


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