GET THE APP

Stability indicating nature of RP-HPLC method for determination of impurity profile in malathion | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

Abstract

Stability indicating nature of RP-HPLC method for determination of impurity profile in malathion

Author(s): Veera Reddy. Arava, Madhusudhan Reddy. Bethi, Kameshwar Rao. Cherukuri, Gopichand. Thota and Sanjeeva Reddy.Cherukupally.

The objective of the present work was to develop stability indicating RP-HPLC method for determination of impurities in Malathion on YMC-Pack ODS AQ 250 X 4.6mm 5μm column using a gradient mixture of solvent A ( Milli Q water, adjust the pH of the above solution to 2.5 using Orthophosphoric acid) and solvent B (Methanol). The flow rate is 0.7ml/min and the detection wavelength is 210nm. Statistical analysis proved the method to repeatable, specific and accurate for estimation of Malathion and its impurities. It can be used as a stability indicating method due to its effective separation of the drug from its impurities.


PDF

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Google Scholar citation report
Citations : 23677

Der Pharma Chemica received 23677 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry