GET THE APP

Studies on binding modes between salivary amylase-food dyes and effect of Copper ions: molecular docking approach | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

Abstract

Studies on binding modes between salivary amylase-food dyes and effect of Copper ions: molecular docking approach

Author(s): Ismail. Daoud, Mourad. Mesmoudi and Said. Ghalem

The interaction between metal ions and the oral environment is a major subject matter in dental research. The saliva acts as an electrolyte solution for different dental alloys. Saliva is expected to be of significance for the perception of food stimuli in the mouth. Mixing the food with saliva, including breakdown and dilution, is considered to be of large importance for semi-solids as these products are masticated without chewing, Saliva contains a range of enzymes that are susceptible to proteolysis. α-Amylase, present in large concentrations in whole saliva (WS). Starch is hydrolyzed to glucose, maltose and dextrin by α- and β-amylases and other related enzyme. In the other hand the affinity interactions between pigments and saliva were influenced by some factors, such as functional groups, molecular weight of pigments, temperatures, pH values, and salt concentrations. All these factors suggest that the complex of pigments may be difficult to remove from the WS film. The aim of this study was to test the effect of metal ions (copper) released from dental amalgam on the α-amylase activity.


PDF

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Google Scholar citation report
Citations : 23677

Der Pharma Chemica received 23677 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry