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Studies on N-acetylation of anilines with acetyl chloride using phase transfer catalysts in different solvents | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X

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Abstract

Studies on N-acetylation of anilines with acetyl chloride using phase transfer catalysts in different solvents

Author(s): S. S.Praveen Kumar Darsi, K. S. Nagamani, B. Rama Devi, A. Naidu and P. K. Dubey

Studies on N-acetylation of anilines with acetyl chloride in the prescence of a base like K2CO3 and phase transfer catalysts like TBAB, TEBAC and D-Glucose in different solvents like DMF, DMSO, acetonitrile, ethyl acetate, chloroform etc at RT have been carried out . Phase Transfer Catalyzed (TBAB) N-acetylation of anilines with acetyl chloride in DMF as solvent and K2CO3 as base is considered to be efficient and convenient synthetic methodology


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