Studies on preparation of 2-Acetylbenzimidazole | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.


Studies on preparation of 2-Acetylbenzimidazole

Author(s): P.Kishore Kumar, P. K. Dubey

o-Phenylenediamine (1) was condensed with lactic acid (2) under Philips conditions to obtain the previously known 2-(α-hydroxyethyl)benzimidazole (3). Oxidation of 3 with K2Cr2O7 in dil. H2SO4 using the literature method gave the previously reported 2-acetylbenzimidazole (4). Several methods have been tried using various oxidising agents / dehydrogenating agents to optimise the preparation of 4 from 3.


Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Google Scholar citation report
Citations : 25868

Der Pharma Chemica received 25868 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry