Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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Abstract

Studies on some 2-methoxybenzohydroxamate complexes of aryltellurium(IV) and diaryltellurium(IV)

Author(s): Sonu Chauhan, Deepak, Sapana Garg and Krishan K. Verma

Twelve new complexes of the 2- methoxybenzohydroxamate with aryltellurium(IV) and diaryltellurium(IV) of type RTeCl2(L), RTeCl(L)2, R2TeCl(L) and R2Te(L)2; (where R = p-methoxyphenyl, p-hydroxyphenyl, 3-methyl-4- hydroxyphenyl and L = 2-methoxybenzo- hydroxamate) have been synthesized by reactions of potassium 2- methoxybenzohydroxamate with corresponding aryltellurium(IV) chlorides . They have been characterized by elemental analyses, molar conductance, infrared and proton magnetic resonance spectroscopy. The spectral studies predict the uninegative bidentate [O, O’] nature of the ligand to give penta- and hexa- coordinated tellurium (IV) complexes. The complexes also have been screened for their antimicrobial activity against various bacteria and fungi organisms and it has been observed that some of these possess substantial antimicrobial activity.


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