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Synthesis and Antibacterial Activity of 2-{2-[(4-`chlorophenyl)sulfanyl]ethoxy}-3-methoxy-5-[6-(3,4,5-trimethoxyphenyl)-3- pyridazinyl]benzonitrile | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X

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Abstract

Synthesis and Antibacterial Activity of 2-{2-[(4-`chlorophenyl)sulfanyl]ethoxy}-3-methoxy-5-[6-(3,4,5-trimethoxyphenyl)-3- pyridazinyl]benzonitrile

Author(s): Srinuvasu N, Monalisa Boruah, Balram Ba, Ram B,Taara B

The present paper describes the synthesis of the title compound, which is a hybrid scaffold of our earlier reported work on 2,5-diaryltetrahydrofuran, utilizing an inexpensive commercially available vanillin as starting material, in over all eight steps. The newly synthesized title compound, displayed excellent to moderate activity towards the bacterial strains tested.


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