Synthesis and antifungal studies of bis-mono and difluorophenacyl azolium compounds | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.


Synthesis and antifungal studies of bis-mono and difluorophenacyl azolium compounds

Author(s): Dhanraj T. S. S. Sundaram, Jayati Mitra, Aminul Islam, B. Venkateswara Rao, S.Paul Douglas

A new series of novel bis-mono and difluorophenacyl triazolium and imidazolium compounds were synthesized starting from mono and difluorophenacyl chloride, 1H-1,2,4-triazole and 1H-imidazole. Similarly, 4-amino mono and difluorophenacyl triazolium compounds were prepared from 4-amino-4H-1,2,4-triazole and mono and difluorophenacyl chloride. A comparative study of these compounds against the fungi (aspergillus niger, aspergillus flavus and penicillium chrysogenum) were screened, while keeping Amphotericin B as standard. The antifungal tests have shown that most of the synthesized azolium compounds exhibit slight to moderate activity against the selected fungi.


Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Recommended Conferences
Google Scholar citation report
Citations : 23677

Der Pharma Chemica received 23677 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry