Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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Abstract

Synthesis and antimicrobial activities of some new pyrazole derivatives

Author(s): N.V Kavitha, Kalpana Divekar, Brahmani Priyadarshini , S. Gajanan. M. Manjunath

Chloro acetyl and Acetyl pyrazoline derivatives have been synthesised by the condensation of pyrazoline derivatives (obtained by the reaction of various chalcones with hydrazine hydrate) with chloroacetyl chloride and glacial acetic acid respectively. The structures of new compounds were established on the basis of elemental IR and H1NMR data, the compounds were evaluated for their antibacterial activities.


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