GET THE APP

Synthesis and antimicrobial activity evaluation of new dialkyl heteroarylphosphonates | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X

ilbet

süperbetin giriş

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

agariookey oyna istanbul okey

Abstract

Synthesis and antimicrobial activity evaluation of new dialkyl heteroarylphosphonates

Author(s): K.Venkata Ramana, K. C. Venkata Subbaiah, V. Lokanatha and C. Naga Raju

Synthesis of new dialkyl heteroaryl phosphonates (4a-f and 5a-f) is accomplished with high yields via Michaelis-Arbuzov rearrangement by the reaction of various heteroaryl halides with triethyl /triisopropyl phosphite at 50-55 °C in dry tetrahydrofuran (THF) in the presence of BF3.Et2O as a catalyst. The structures of the title compounds were established by elemental analysis and spectral data (IR, 1H, 13C and 31P NMR and LC- mass) and their antimicrobial activity was evaluated. The title compounds exhibited moderate antimicrobial activity.


PDF

rokettube brazzers

Turkish dental care is known to be affordable compared to other countries. If you want an affordible dentist Turkey, check out periodonta. It is heavily recommended for dental patients visiting Turkey