Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

Abstract

Synthesis and antimicrobial activity of chalcones of naphtho[2,1- b]furan condensed with barbituric acid

Author(s): Chandrashekhar C.H, Latha K.P, Vagdevi H. M and Vaidya V.P

Barbitones were synthesized by the condensation of chalcones with barbituric acid. The stuctures of the synthesized compounds assigned on the basis of elemental analysis, IR, 1H NMR and mass spectral studies. All the products were evaluated for their in vitro antimicrobial activity against various strains of bacteria and fungi.


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