Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.


Synthesis and antimicrobial activity of novel falvonols

Author(s): Gurubasavaraja Swamy. P. M., Rajendra Prasad. Y., B. S. Sastry, Giles. D.,Gurumurthy. M. and Agasimundin. Y. S

A novel series of falvonols (16a-s) were synthesized by the reaction of respective chalcones (2a-s) and hydrogen peroxide. The structures of all the compounds were confirmed by spectral data and tested for their antimicrobial activities against both gram positive B.subtilis, gram negative E.coli bacteria and antifungal activity against P.notatum C. tropicalis, A. niger and C. albicans by using cup plate method. Among the synthesized compounds, Flavanol derivatives bearing electron releasing functional group (16b, 16n and 16s) showed good activity against E.Coli . Derivative bearing dimethoxy group (16n) showed good activity againest B. Subtilis. Flavonol derivatives showed moderate to weak activity against A. niger, C. albicans and Penicillium notatum fungi.


SCImago Journal & Country Rank
Recommended Conferences
bornova escort karşıyaka escort osmangazi escort buca escort anne porno fetiş porno anal porno bartın escort burdur escort eskişehir escort escort izmir bursa escort porno escort bayan