GET THE APP

Synthesis and antimicrobial activity of phthalazine substituted 1,2,4-triazolo- [3,4-b]-1,3,4-thiadiazoles and 7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

Abstract

Synthesis and antimicrobial activity of phthalazine substituted 1,2,4-triazolo- [3,4-b]-1,3,4-thiadiazoles and 7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines

Author(s): A. M Sridhara, K. R Venugopala Reddy, J. Keshavayya, B. Chidananda , Yaragola Prasad , G. Satish Kumar , S.G. Vadiraj, Prosenjit Bose, Sanath Kumar Goud , S.K.Peethambar

A series of 3,6-disubstituted 1,2,4–triazolo[3,4-b]-1,3,4-thiadiazoles and 7H-[1,2,4] triazolo[3,4-b][1,3,4]thiadiazine were synthesized from methyl {3-[(6-chloropyridin-3- yl)methyl]-4-oxo-3,4-dihydrophthalazin-1-yl}acetate in multiple steps. Most of the newly synthesized compounds were screened for their antimicrobial activity against variety of human pathogenic bacteria’s. Many of the compounds were found to be potent as antimicrobials


PDF

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank