Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.


Synthesis and antimicrobial activity of some new 3, 4-disubstituted pyrroles and pyrazoles

Author(s): Syamaiah K. 1 , Durgamma S. 1 , Sudheer K. 2 , Padmavathi V. 1 and Padmaja A. 1 *

Some new 3,4-disubstituted pyrroles and pyrazoles w ere prepared from the synthetic intermediate (E)-1- (4-(m- chlorobenzyloxy)-3-methoxyphenyl)-3-(4-aryl)prop-2- en-1-one on treatment with tosylmethyl isocyanide a nd diazomethane. All the target compounds were evaluat ed for antimicrobial activity. The chloro substitut ed pyrroles and pyrazoles ( 5c , 7c ) exhibited pronounced antimicrobial activity parti cularly against S. aureus and P. chrysogenum


SCImago Journal & Country Rank
Recommended Conferences
bornova escort karşıyaka escort osmangazi escort buca escort anne porno fetiş porno anal porno bartın escort burdur escort eskişehir escort escort izmir bursa escort porno escort bayan