GET THE APP

Synthesis and antimicrobial evaluation of thiadiazole derivatives | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

Abstract

Synthesis and antimicrobial evaluation of thiadiazole derivatives

Author(s): US Baghel, H Kaur*, A Chawla and RK Dhawan

A new series of thiadiazole derivatives were synthesized and screened for their antimicrobial activity. All the newly synthesized compounds were screened for their antibacterial activity against Gram positive species Bacillus subtilis, Staphylococcus aureus and Gram negative species Pseudomonas aeruginosa, E. coli and Candida albicans, A. niger species were used as organism for antifungal activity. Compounds 5c and 5e shows potent activity against the test bacteria and fungi, and emerged as potential molecules for further development. Compounds having substituted phenyl ring were found more biological active and compounds having phenyl ring substituted with electron withdrawing groups gives highest antimicrobial activity.


PDF

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Google Scholar citation report
Citations : 23677

Der Pharma Chemica received 23677 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry